Satoru Yokoyama Selected Research

hirsutine

7/2016	Targeting the ataxia telangiectasia mutated pathway for effective therapy against hirsutine-resistant breast cancer cells.
4/2015	Selective anticancer activity of hirsutine against HER2‑positive breast cancer cells by inducing DNA damage.

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Satoru Yokoyama Research Topics

Disease

27	Neoplasms (Cancer) 01/2022 - 12/2009
15	Melanoma (Melanoma, Malignant) 12/2021 - 01/2006
11	Breast Neoplasms (Breast Cancer) 01/2022 - 05/2013
9	Neoplasm Metastasis (Metastasis) 11/2020 - 12/2010
6	Lung Neoplasms (Lung Cancer) 10/2016 - 12/2009
5	Hypoxia (Hypoxemia) 11/2013 - 12/2005
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2016 - 07/2014
3	Pancreatic Neoplasms (Pancreatic Cancer) 11/2013 - 06/2012
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 07/2013 - 11/2008
2	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 09/2020
2	Clear Cell Sarcoma 10/2011 - 08/2008
1	Endometrial Neoplasms (Endometrial Cancer) 01/2022
1	Inflammation (Inflammations) 12/2021
1	Edema (Dropsy) 04/2021
1	Hypertension (High Blood Pressure) 04/2021
1	Diabetes Mellitus 04/2021
1	Bites and Stings (Sting) 01/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	Necrosis 12/2020
1	Microcephaly 12/2018
1	Autoimmune Diseases (Autoimmune Disease) 06/2018
1	Communicable Diseases (Infectious Diseases) 06/2018
1	Ataxia Telangiectasia (Louis Bar Syndrome) 07/2016
1	Obesity 01/2015

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 10/2016 - 12/2005
6	LigandsIBA 12/2020 - 05/2013
5	ErbB Receptors (EGF Receptor)IBA 01/2022 - 07/2014
5	Pharmaceutical PreparationsIBA 01/2020 - 08/2008
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2014 - 01/2012
4	Microphthalmia-Associated Transcription FactorIBA 11/2011 - 10/2006
3	Monoclonal AntibodiesIBA 01/2022 - 09/2013
3	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 03/2015
3	Indicators and Reagents (Reagents)IBA 11/2020 - 08/2014
3	Messenger RNA (mRNA)IBA 07/2009 - 01/2006
2	Temozolomide (Temodar)FDA LinkGeneric 01/2022 - 01/2021
2	SOXE Transcription FactorsIBA 12/2021 - 10/2006
2	Histone Deacetylase InhibitorsIBA 12/2021 - 08/2008
2	epidermal growth factor receptor VIIIIBA 01/2021 - 09/2020
2	Proteasome Endopeptidase Complex (Proteasome)IBA 11/2020 - 04/2018
2	Deubiquitinating EnzymesIBA 11/2020 - 04/2018
2	UbiquitinIBA 11/2020 - 04/2018
2	Small Interfering RNA (siRNA)IBA 11/2020 - 12/2009
2	PhytochemicalsIBA 01/2020 - 04/2015
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2019 - 03/2015
2	Biological ProductsIBA 12/2018 - 03/2014
2	BerberineIBA 07/2017 - 09/2013
2	hirsutineIBA 07/2016 - 04/2015
2	Phosphotransferases (Kinase)IBA 07/2016 - 07/2015
2	Gefitinib (Iressa)FDA Link 01/2016 - 07/2014
2	Tyrosine Kinase InhibitorsIBA 01/2016 - 07/2014
2	Propolis (Bee Bread)IBA 11/2013 - 07/2013
2	chrysinIBA 11/2013 - 07/2013
2	Prolyl-Hydroxylase InhibitorsIBA 10/2011 - 11/2008
2	heme oxygenase-2IBA 01/2010 - 07/2009
2	Heme (Haem)IBA 11/2008 - 12/2005
2	Endothelin Receptors (Endothelin Receptor)IBA 10/2006 - 04/2006
1	Tamoxifen FDA LinkGeneric 01/2022
1	Estrogen ReceptorsIBA 01/2022
1	Cetuximab (Erbitux)FDA Link 01/2022
1	Panitumumab (Vectibix)FDA Link 01/2022
1	Interleukin-3 (Interleukin 3)IBA 12/2021
1	Interleukin-5 (Interleukin 5)IBA 12/2021
1	pregna-4,17-diene-3,16-dione (guggulsterone)IBA 08/2021
1	Imiquimod (Aldara)FDA LinkGeneric 04/2021
1	Toll-Like Receptors (Toll-Like Receptor)IBA 04/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	SB 203580IBA 01/2021
1	Monounsaturated Fatty AcidsIBA 01/2021
1	Firefly LuciferasesIBA 12/2020
1	ATP dependent 26S protease (26S proteasome)IBA 11/2020
1	VemurafenibIBA 11/2020
1	Adenosine Triphosphatases (ATPase)IBA 11/2020
1	Tyrosine (L-Tyrosine)FDA Link 09/2020
1	flavoneIBA 01/2020
1	baicaleinIBA 01/2020
1	dinaciclibIBA 01/2020
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2020
1	InterleukinsIBA 01/2020
1	Drug CombinationsIBA 01/2020
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2020
1	Carrier Proteins (Binding Protein)IBA 12/2018
1	CytokinesIBA 06/2018
1	InterferonsIBA 06/2018
1	Transcription Factors (Transcription Factor)IBA 04/2018
1	Ligases (Synthetase)IBA 04/2018
1	COP9 Signalosome ComplexIBA 04/2018
1	LuciferasesIBA 04/2017
1	Etoposide (VP 16)FDA LinkGeneric 04/2017
1	saikosaponin DIBA 04/2017
1	Connective Tissue Growth FactorIBA 10/2016
1	AlkaloidsIBA 07/2016
1	EphA2 ReceptorIBA 07/2015
1	tyrosine receptor (receptor, tyrosine)IBA 07/2015
1	A-Form DNA (A-DNA)IBA 04/2015
1	keishibukuryoganIBA 01/2015

Therapy/Procedure

12	Therapeutics 12/2021 - 08/2008
3	Drug Therapy (Chemotherapy) 04/2017 - 08/2014
2	Traditional Medicine (Folk Remedies) 04/2021 - 12/2013
1	Immunotherapy 12/2021
1	Kampo Medicine (Kampo) 01/2015